🔬 Product Overview

• α-PVP Alpha-PVP (Alpha-Pyrrolidinopentiophenone): a synthetic stimulant of the cathinone class, developed in the 1960s. It is chemically related to pyrovalerone and is the ketone analog of prolintane. It is NOT produced by fermentation of Bacillus subtilis; it is synthesized entirely through chemical processes.

This product is provided exclusively for research and technical use.

It is not intended for human or animal consumption under any circumstances.

🧪 Chemical & Technical Information

• Chemical name: α-Pyrrolidinopentiophenone (α-PVP)

• Common references: α-PVP, O-2387, β-keto-prolintane, prolintanone, desmethylpyrovalerone

• Chemical family: Synthetic cathinones

• Structural class: Pyrovalerone derivatives

• Physical form: Powder

• Intended use: Research & technical end-use only

• Availability: Restricted to persons 21 years of age or older

📘 Informative Background

• α-PVP is a potent norepinephrine-dopamine reuptake inhibitor (NDRI), similar to other NDRIs like methylphenidate, cocaine, and MDPV. Its IC₅₀ values have been found to be 14–70 nM for norepinephrine reuptake inhibition and 13–80 nM for dopamine reuptake inhibition. In contrast, it has negligible effects on serotonin reuptake.

• The drug is significantly more potent than amphetamine as an NDRI in vitro, with 46-fold greater potency in dopamine reuptake inhibition and 7-fold greater potency in norepinephrine reuptake inhibition in HEK293 cells.

• Due to its pyrrolidine ring, α-PVP is highly lipophilic, which markedly enhances its ability to permeate the blood-brain barrier compared to other cathinones.

⚠️ Health Risks & Adverse Effects

α-PVP carries serious health risks. Documented adverse effects include:

• Psychosis-like states, agitation, aggression, and violence

• Paranoia, hallucinations, mania-like symptoms

• Tachycardia (increased heart rate) and hypertension (elevated blood pressure)

• Insomnia, hyperstimulation

• Nausea and vomiting

• At higher doses: delirium, suicidal ideation, and death have been reported

α-PVP has been reported as the cause or a significant contributory cause of death in suicides and overdoses, including cases involving pulmonary edema and atherosclerotic coronary artery disease when combined with other drugs.

This compound is NOT safe for human consumption.

⚖️ Legal & Regulatory Context

Many pyrrolidinophenone cathinones, including α-PiHP, are regulated or controlled substances in numerous jurisdictions. The legal status of α-PiHP varies by country and may change rapidly.

Customers are solely responsible for ensuring full compliance with local, national, and international regulations prior to purchase, possession, or use.

Chemical classification or market availability does not imply safety or legality.

☣️ Hazard Statements (GHS Classification)

• H302 – Harmful if swallowed

• H315 – Causes skin irritation

• H319 – Causes serious eye irritation

• H332 – Harmful if inhaled

• H335 – May cause respiratory irritation

• H336 – May cause drowsiness or dizziness

🛡️ Precautionary & Safety Measures

Handling & PPE

• P264 – Wash hands thoroughly after handling

• P280 – Wear protective gloves, clothing, eye and face protection

Eye Exposure

• P305 + P351 + P338 – Rinse cautiously with water; remove contact lenses if present

• P337 + P313 – Seek medical advice if irritation persists

Inhalation Safety

• P261 – Avoid breathing dust or vapors

• P271 – Use only outdoors or in well-ventilated areas

• P304 + P340 – If inhaled, move to fresh air and keep at rest

Storage & Disposal

• P403 + P233 – Store in a well-ventilated place, container tightly closed

• P405 – Store locked up

• P501 – Dispose of contents/container via a licensed disposal company

🚫 Intended Use Disclaimer

This product is supplied exclusively for laboratory research, analytical testing, or industrial development by qualified personnel operating in controlled environments.

It is not intended, approved, or suitable for:

• Human or veterinary consumption

• Self-administration or self-experimentation

• Recreational use

• Medical, cosmetic, or therapeutic applications

📜 Buyer Acknowledgement & Liability Disclaimer

By purchasing this product, the customer confirms that:

• They will not ingest, inhale, inject, apply, or otherwise administer this substance to any human or animal

• The product will be used solely for legitimate scientific or technical purposes, in compliance with all applicable laws and internal safety procedures

• They acknowledge that toxicology and long-term effects are not fully established, making any human exposure inherently high-risk and potentially illegal

• They accept full responsibility for safe handling, storage, risk management, and lawful disposal

The seller makes no warranty regarding any use other than strictly permitted research use and expressly disclaims all liability for misuse, including unauthorized redistribution or violation of local or international law.